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Technology Overview

REG Life Sciences is developing an industrial biotechnology platform for the cost competitive production of sustainable products for the chemical and fuel markets. The heart of the technology lies in its biological catalysts, which have been engineered to selectively convert abundant renewable feedstocks, from corn and cane sugars to crude glycerin from biodiesel production and cellulosic sugars, directly to drop-in and differentiated products. To create these catalysts, REG Life Sciences applies synthetic biology to combine the highly efficient metabolism of microorganisms with new biocatalytic capabilities engineered into each cell. The resulting catalysts selectively and efficiently convert feedstocks to a final product in a single-step fermentation process. The product is secreted from the cell where it conveniently forms a light organic phase for recovery. Our proprietary technology is designed to enable multiple products to be produced from the same fermenter in cost-competitive processes.

REG Life Sciences is harnessing the powerful catalytic capabilities of microbial metabolism. Unique sequences of DNA enable chemical transformations in a cell by harnessing the power of enzymes. A “metabolic pathway” is composed of a set of these enzymes working together to sequentially convert one compound in the cell (feedstock), through a series of selective chemical transformations, to a different compound (a renewable chemical). REG Life Sciences has identified what we believe is the most efficient industrial biotechnology method for the synthesis of hydrocarbon chains – fatty acid biosynthesis – and is combining that discovery with new engineered biochemical pathways that convert a wide range of feedstocks into high performance chemicals and advanced biofuels. By engineering all of the catalytic steps into a single microbial catalyst, REG Life Sciences seeks to enable a simple, selective conversion processes to targeted products.